| Coolant Brand | Coolant Model | Recommendation |
| CORSAIR | XL5 Performance Coolant | Preferred |
| CORSAIR | XL8 Performance Coolant | Preferred |
| Aquacomputer | Double Protect Ultra | Compatible |
| Coolaboratory | Liquid Coolant Pro | Compatible |
| EK | Cryofuel | Compatible |
| Jingway | Iceland X | Compatible |
| Koolance | LIQ-702 | Compatible |
| Liquid Cool | CFX Opaque | Compatible |
| Mayhems | IDC | Compatible |
| Mayhems | Pastel | Compatible |
| Mayhems | X1 | Compatible |
| Mayhems | XT-1 Nuke | Compatible |
| Mayhems | XT-1 | Compatible |
| Nanoxia | Cooling Fluid Pro | Compatible |
| Nanoxia | Cooling Fluid Pro Opaque | Compatible |
| Primochill | TRUE | Compatible |
| Thermaltake | C1000 | Compatible |
| XSPC | EC6 | Compatible |
| XSPC | ECX | Compatible |
| Alphacool | Eiswasser | Not compatible |
| Alphacool | Eiswasser Pastel | Not compatible |
| Alphacool | Cape Kelvin Catcher CKC | Not compatible |
| Aquatuning | AT-Protect | Not compatible |
| EK | Cryofuel Solid | Not compatible |
| EK | Cryofuel Mystic Fog | Not compatible |
| Jingway | Galaxy | Not compatible |
| Mayhems | SFX Aurora | Not compatible |
| Mayhems | XTR | Not compatible |
| Phobya | ZuperZero Xtreme | Not compatible |
| Primochill | Opaque | Not compatible |
| Primochill | Liquid Utopia | Not compatible |
| Primochill | VUE | Not compatible |
| Swiftech | HydrX | Not compatible |
| Thermaltake | C1000 Opaque | Not compatible |
| Thermaltake | Coolant 1000 | Not compatible |
| XSPC | EC6 Opaque | Not compatible |
| UFO Technologies | Cryo-Chillz | Not compatible |
Internal testing identified incompatibilities between certain liquid coolants and Hydro X Series products. Detailed information regarding specific incompatibilities is either unavailable or not publicly disclosed. Any coolant not explicitly listed as compatible should be considered incompatible.